Yes — with 42.7 GB to spare

Qwen2.5-Coder 7B at Q4_K_M fits your Ryzen AI Max+ 395 · 64 GB entirely in unified memory at 8K context, at an estimated 33 tokens per second. There is room for its full 128K window.

Fully in unified memory 8K context Q4_K_M · 4.3 GB Apache 2.0 Released Nov 2024

The standard local autocomplete model — small enough to keep resident all day, and still the best FIM model under 8B.

What hardware do I need for Qwen2.5-Coder 7B? →

The VRAM budget

weights 4.3 GB
Weights 4.3 GB KV cache @ 8K 0.44 GB Runtime overhead 0.6 GB Free 42.7 GB of 48.0 GB

Quantisation ladder

QuantWeightsTotal @ 8KMax contextTok/sQualityFit
F16 14.2 GB 15.2 GB 128K 10 Reference Long context
Q8_0 7.5 GB 8.6 GB 128K 19 −0.1% ppl Long context
Q6_K 5.8 GB 6.9 GB 128K 25 −0.4% ppl Long context
Q5_K_M 5.0 GB 6.1 GB 128K 28 −0.8% ppl Long context
Q4_K_M 4.3 GB 5.3 GB 128K 33 −1.9% ppl Recommended
Q3_K_M 3.5 GB 4.5 GB 128K 41 −5.4% ppl Long context
Q2_K 3.0 GB 4.0 GB 128K 48 −15% ppl Long context

Quality is the published perplexity delta against f16 weights. Max context assumes an f16 KV cache; q8_0 roughly doubles it.

How to run it

terminal
$ ollama pull qwen2.5-coder:7b
$ OLLAMA_CONTEXT_LENGTH=8192 \
    ollama run qwen2.5-coder:7b

The default. One binary, a model registry, an OpenAI-compatible port. More on Ollama.

01Download is 4.3 GB. Keep it on an SSD — a first load off a spinning disk takes minutes.
02macOS caps what the GPU may wire down at about 48.0 GB of 64 GB. Raising it with iogpu.wired_limit_mb is possible, and risky.
03There is room to go to the model's full 128K context on this card.
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