Yes — with 27.0 GB to spare

Qwen2.5-Coder 32B at Q4_K_M fits your Ryzen AI Max+ 395 · 64 GB entirely in unified memory at 8K context, at an estimated 7.8 tokens per second. Past 115K the KV cache pushes it over — quantise the cache to q8_0, or step down a quantisation, to go longer.

Fully in unified memory 8K context Q4_K_M · 18.4 GB Apache 2.0 Released Nov 2024

The first local code model that felt competitive with hosted assistants. Qwen3.8 27B is smaller and far ahead on agentic work.

What hardware do I need for Qwen2.5-Coder 32B? →

The VRAM budget

weights 18.4 GB
Weights 18.4 GB KV cache @ 8K 2.00 GB Runtime overhead 0.6 GB Free 27.0 GB of 48.0 GB

Quantisation ladder

QuantWeightsTotal @ 8KMax contextTok/sQualityFit
Q8_0 32.5 GB 35.1 GB 59K 4.4 −0.1% ppl Long context
Q6_K 25.0 GB 27.6 GB 89K 5.7 −0.4% ppl Long context
Q5_K_M 21.7 GB 24.3 GB 102K 6.6 −0.8% ppl Long context
Q4_K_M 18.4 GB 21.0 GB 115K 7.8 −1.9% ppl Recommended
Q3_K_M 14.9 GB 17.5 GB 128K 9.6 −5.4% ppl Long context
Q2_K 12.8 GB 15.4 GB 128K 11 −15% ppl Long context

Quality is the published perplexity delta against f16 weights. Max context assumes an f16 KV cache; q8_0 roughly doubles it.

How to run it

terminal
$ ollama pull qwen2.5-coder:32b
$ OLLAMA_CONTEXT_LENGTH=8192 \
    ollama run qwen2.5-coder:32b

The default. One binary, a model registry, an OpenAI-compatible port. More on Ollama.

01Download is 18.4 GB. Keep it on an SSD — a first load off a spinning disk takes minutes.
02macOS caps what the GPU may wire down at about 48.0 GB of 64 GB. Raising it with iogpu.wired_limit_mb is possible, and risky.
03There is room to go to 115K context on this card.
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