Yes — with 28.3 GB to spare

Mistral Small 4 119B-A6B at Q4_K_M fits your Ryzen AI Max+ 395 · 128 GB entirely in unified memory at 8K context, at an estimated 18 tokens per second. There is room for its full 256K window.

Fully in unified memory 8K context Q4_K_M · 66.9 GB Apache 2.0 Released 17 Mar 2026 Vision Not in the Ollama library

Instruct, reasoning, vision and code in one 119B MoE. A latent KV cache (320 wide) keeps context cheap; the weights still want 64 GB+.

What hardware do I need for Mistral Small 4 119B-A6B? →

The VRAM budget

weights 66.9 GB
Weights 66.9 GB KV cache @ 8K 0.18 GB Runtime overhead 0.6 GB Free 28.3 GB of 96.0 GB

Quantisation ladder

QuantWeightsTotal @ 8KMax contextTok/sQualityFit
Q8_0 117.8 GB 118.5 GB ~10 −0.1% ppl 22.5 GB over
Q6_K 90.9 GB 91.7 GB 205K 13 −0.4% ppl Long context
Q5_K_M 78.5 GB 79.3 GB 256K 16 −0.8% ppl Long context
Q4_K_M 66.9 GB 67.7 GB 256K 18 −1.9% ppl Recommended
Q3_K_M 54.2 GB 54.9 GB 256K 23 −5.4% ppl Long context
Q2_K 46.4 GB 47.2 GB 256K 26 −15% ppl Long context

Quality is the published perplexity delta against f16 weights. Max context assumes an f16 KV cache; q8_0 roughly doubles it. This model uses multi-head latent attention, so its cache is a compressed latent rather than full K and V.

How to run it

terminal
$ llama-server \
    -hf mistralai/Mistral-Small-4-119B-2603:Q4_K_M \
    -c 8192 -ngl 99

The engine underneath most of the others. Every knob is exposed. More on llama.cpp.

01Download is 66.9 GB. Keep it on an SSD — a first load off a spinning disk takes minutes.
02macOS caps what the GPU may wire down at about 96.0 GB of 128 GB. Raising it with iogpu.wired_limit_mb is possible, and risky.
03There is room to go to the model's full 256K context on this card.
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