Yes — with 41.3 GB to spare
Ministral 3 8B at Q4_K_M fits your Ryzen AI Max+ 395 · 64 GB entirely in unified memory at 8K context, at an estimated 29 tokens per second. There is room for its full 256K window.
Fully in unified memory
8K context
Q4_K_M · 5.0 GB
Apache 2.0
Released Dec 2025
Vision
Mistral's 8B with images in. Plain GQA, so budget more KV cache than Qwen3.5 9B at the same context.
The VRAM budget
weights 5.0 GB
Weights 5.0 GB
KV cache @ 8K 1.06 GB
Runtime overhead 0.6 GB
Free 41.3 GB of 48.0 GB
Quantisation ladder
| Quant | Weights | Total @ 8K | Max context | Tok/s | Quality | Fit |
|---|---|---|---|---|---|---|
| F16 | 16.6 GB | 18.3 GB | 231K | 8.6 | Reference | Long context |
| Q8_0 | 8.8 GB | 10.5 GB | 256K | 16 | −0.1% ppl | Long context |
| Q6_K | 6.8 GB | 8.5 GB | 256K | 21 | −0.4% ppl | Long context |
| Q5_K_M | 5.9 GB | 7.6 GB | 256K | 24 | −0.8% ppl | Long context |
| Q4_K_M | 5.0 GB | 6.7 GB | 256K | 29 | −1.9% ppl | Recommended |
| Q3_K_M | 4.1 GB | 5.7 GB | 256K | 35 | −5.4% ppl | Long context |
| Q2_K | 3.5 GB | 5.1 GB | 256K | 41 | −15% ppl | Long context |
Quality is the published perplexity delta against f16 weights. Max context assumes an f16 KV cache; q8_0 roughly doubles it.
How to run it
$ ollama pull ministral-3:8b $ OLLAMA_CONTEXT_LENGTH=8192 \ ollama run ministral-3:8b
The default. One binary, a model registry, an OpenAI-compatible port. More on Ollama.
01Download is 5.0 GB. Keep it on an SSD — a first load off a spinning disk takes minutes.
02macOS caps what the GPU may wire down at about 48.0 GB of 64 GB. Raising it with iogpu.wired_limit_mb is possible, and risky.
03There is room to go to the model's full 256K context on this card.