Yes — with 90.8 GB to spare

Gemma 4 E4B at Q4_K_M fits your Ryzen AI Max+ 395 · 128 GB entirely in unified memory at 8K context, at an estimated 32 tokens per second. There is room for its full 128K window.

Fully in unified memory 8K context Q4_K_M · 4.5 GB Apache 2.0 Released 2 Apr 2026 Vision

The laptop Gemma. 4.5B effective, 8B on disk; a single KV head per window layer keeps its cache tiny.

What hardware do I need for Gemma 4 E4B? →

The VRAM budget

weights 4.5 GB
Weights 4.5 GB KV cache @ 8K 0.14 GB Runtime overhead 0.6 GB Free 90.8 GB of 96.0 GB

Quantisation ladder

QuantWeightsTotal @ 8KMax contextTok/sQualityFit
F16 14.9 GB 15.6 GB 128K 9.6 Reference Long context
Q8_0 7.9 GB 8.7 GB 128K 18 −0.1% ppl Long context
Q6_K 6.1 GB 6.9 GB 128K 23 −0.4% ppl Long context
Q5_K_M 5.3 GB 6.0 GB 128K 27 −0.8% ppl Long context
Q4_K_M 4.5 GB 5.2 GB 128K 32 −1.9% ppl Recommended
Q3_K_M 3.6 GB 4.4 GB 128K 39 −5.4% ppl Long context
Q2_K 3.1 GB 3.9 GB 128K 46 −15% ppl Long context

Quality is the published perplexity delta against f16 weights. Max context assumes an f16 KV cache; q8_0 roughly doubles it. This model interleaves sliding-window layers (512 tokens, 7 of 42 layers global), which is why its cache barely grows with context.

How to run it

terminal
$ ollama pull gemma4:e4b
$ OLLAMA_CONTEXT_LENGTH=8192 \
    ollama run gemma4:e4b

The default. One binary, a model registry, an OpenAI-compatible port. More on Ollama.

01Download is 4.5 GB. Keep it on an SSD — a first load off a spinning disk takes minutes.
02macOS caps what the GPU may wire down at about 96.0 GB of 128 GB. Raising it with iogpu.wired_limit_mb is possible, and risky.
03There is room to go to the model's full 128K context on this card.
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