Yes — with 32.7 GB to spare
Devstral Small 2 24B at Q4_K_M fits your Ryzen AI Max+ 395 · 64 GB entirely in unified memory at 8K context, at an estimated 11 tokens per second. Past 216K the KV cache pushes it over — quantise the cache to q8_0, or step down a quantisation, to go longer.
Fully in unified memory
8K context
Q4_K_M · 13.5 GB
Apache 2.0
Released Dec 2025
Vision
Not in the Ollama library
Built for software-engineering agents (OpenHands, Cline). Dense 24B, 384K window. Not in the Ollama library.
The VRAM budget
weights 13.5 GB
Weights 13.5 GB
KV cache @ 8K 1.25 GB
Runtime overhead 0.6 GB
Free 32.7 GB of 48.0 GB
Quantisation ladder
| Quant | Weights | Total @ 8K | Max context | Tok/s | Quality | Fit |
|---|---|---|---|---|---|---|
| Q8_0 | 23.7 GB | 25.6 GB | 151K | 6.0 | −0.1% ppl | Long context |
| Q6_K | 18.3 GB | 20.2 GB | 186K | 7.8 | −0.4% ppl | Long context |
| Q5_K_M | 15.8 GB | 17.7 GB | 201K | 9.0 | −0.8% ppl | Long context |
| Q4_K_M | 13.5 GB | 15.3 GB | 216K | 11 | −1.9% ppl | Recommended |
| Q3_K_M | 10.9 GB | 12.8 GB | 233K | 13 | −5.4% ppl | Long context |
| Q2_K | 9.4 GB | 11.2 GB | 243K | 15 | −15% ppl | Long context |
Quality is the published perplexity delta against f16 weights. Max context assumes an f16 KV cache; q8_0 roughly doubles it.
How to run it
$ llama-server \
-hf mistralai/Devstral-Small-2-24B-Instruct-2512:Q4_K_M \
-c 8192 -ngl 99
The engine underneath most of the others. Every knob is exposed. More on llama.cpp.
01Download is 13.5 GB. Keep it on an SSD — a first load off a spinning disk takes minutes.
02macOS caps what the GPU may wire down at about 48.0 GB of 64 GB. Raising it with iogpu.wired_limit_mb is possible, and risky.
03There is room to go to 216K context on this card.