Yes — with 147.6 GB to spare

DeepSeek-R1-Distill-Llama 70B at Q4_K_M fits your Instinct MI300X entirely on the GPU at 8K context, at an estimated 81 tokens per second. There is room for its full 128K window.

Fully on GPU 8K context Q4_K_M · 39.7 GB MIT / Llama 3.3 Community Released Jan 2025

The strongest of the R1 distills, and the one that most needs 48 GB or more.

What hardware do I need for DeepSeek-R1-Distill-Llama 70B? →

The VRAM budget

weights 39.7 GB
Weights 39.7 GB KV cache @ 8K 2.50 GB Runtime overhead 0.6 GB Free 147.6 GB of 190.4 GB

Quantisation ladder

QuantWeightsTotal @ 8KMax contextTok/sQualityFit
Q8_0 69.9 GB 73.0 GB 128K 46 −0.1% ppl Long context
Q6_K 53.9 GB 57.0 GB 128K 60 −0.4% ppl Long context
Q5_K_M 46.6 GB 49.7 GB 128K 69 −0.8% ppl Long context
Q4_K_M 39.7 GB 42.8 GB 128K 81 −1.9% ppl Recommended
Q3_K_M 32.1 GB 35.2 GB 128K 100 −5.4% ppl Long context
Q2_K 27.5 GB 30.6 GB 128K 117 −15% ppl Long context

Quality is the published perplexity delta against f16 weights. Max context assumes an f16 KV cache; q8_0 roughly doubles it.

How to run it

terminal
$ ollama pull deepseek-r1:70b
$ OLLAMA_CONTEXT_LENGTH=8192 \
    ollama run deepseek-r1:70b

The default. One binary, a model registry, an OpenAI-compatible port. More on Ollama.

01Download is 39.7 GB. Keep it on an SSD — a first load off a spinning disk takes minutes.
02Close anything else holding VRAM. A browser with hardware acceleration can sit on 1–2 GB.
03There is room to go to the model's full 128K context on this card.
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